Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLCG2 All Species: 18.18
Human Site: S1198 Identified Species: 36.36
UniProt: P16885 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16885 NP_002652.2 1265 147870 S1198 E S E E E L Y S S C R Q L R R
Chimpanzee Pan troglodytes XP_001147944 1265 147906 S1198 E S E E E L Y S S C R Q L R R
Rhesus Macaque Macaca mulatta XP_001111677 1265 147898 S1198 E S E E E L Y S S C R Q L R R
Dog Lupus familis XP_546812 1252 146274 E1191 C E M Q P V L E S E E E L Y S
Cat Felis silvestris
Mouse Mus musculus Q8CIH5 1265 147573 S1198 E S E E E L Y S S C R Q L R R
Rat Rattus norvegicus P24135 1265 147716 S1198 E S E E E L Y S S C R Q L R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508105 991 115582 R930 Y S S C R Q L R R R Q E E L N
Chicken Gallus gallus Q2VRL0 637 72514 V576 T F S F T V Q V P E L A L I R
Frog Xenopus laevis Q32NH8 758 87399 V697 E L A L V R F V V E D Y D K T
Zebra Danio Brachydanio rerio A5D6R3 784 89362 K723 M V E D H D H K S K N D F I G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624101 1134 132613 F1073 P Y F A F I R F V V Q D E D M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784329 940 107748 P879 V V N T M D R P E I D V S A A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98 94.4 N.A. 94.1 94.7 N.A. 62.7 20.7 22.1 21.2 N.A. N.A. 40.9 N.A. 32.9
Protein Similarity: 100 99.9 99.2 97 N.A. 97.1 97.3 N.A. 67.8 33.2 37.5 34.9 N.A. N.A. 59.1 N.A. 49
P-Site Identity: 100 100 100 13.3 N.A. 100 100 N.A. 6.6 13.3 6.6 13.3 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 100 100 33.3 N.A. 100 100 N.A. 20 20 20 26.6 N.A. N.A. 13.3 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 0 0 0 0 0 0 0 9 0 9 9 % A
% Cys: 9 0 0 9 0 0 0 0 0 42 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 17 0 0 0 0 17 17 9 9 0 % D
% Glu: 50 9 50 42 42 0 0 9 9 25 9 17 17 0 0 % E
% Phe: 0 9 9 9 9 0 9 9 0 0 0 0 9 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % G
% His: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 9 0 0 0 9 0 0 0 17 0 % I
% Lys: 0 0 0 0 0 0 0 9 0 9 0 0 0 9 0 % K
% Leu: 0 9 0 9 0 42 17 0 0 0 9 0 59 9 0 % L
% Met: 9 0 9 0 9 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 9 % N
% Pro: 9 0 0 0 9 0 0 9 9 0 0 0 0 0 0 % P
% Gln: 0 0 0 9 0 9 9 0 0 0 17 42 0 0 0 % Q
% Arg: 0 0 0 0 9 9 17 9 9 9 42 0 0 42 50 % R
% Ser: 0 50 17 0 0 0 0 42 59 0 0 0 9 0 9 % S
% Thr: 9 0 0 9 9 0 0 0 0 0 0 0 0 0 9 % T
% Val: 9 17 0 0 9 17 0 17 17 9 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 9 0 0 0 0 42 0 0 0 0 9 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _